I have to warn you that you can find that some of the settings are ridiculous - that is because I have tested something and left the settings so I could test it again in future versions. Or you may find different buttons/chords set to do exactly the same - that's because I have 3 different mice which I use with my laptop and only one of them is with 5 buttons and 4 directions wheel, the other 2 are with less buttons and I tried to make it possible to use them more efficiently.
These are my hotkeys:
Alt + 1, 2, 3, 4, 5 - Layer 1, 2, 3, 4, 5
Ctrl + ` - Open settings window
Ctrl + F1 - Enable/Disable XMBC
Shift + F1 - Toggle Debug mode
I pretty much like to set things in such way, that if I have to switch to another layer (2, 3, 4 or 5) - the setting in it ends up with {Layer:1} so it automatically switches back to layer 1 after the sequence I need is completed. It is very convenient. Also in excel I have chording RMB+LMB in layer 1 that ends up with {Layer:2}, at that point I enter a letter and again I do RMB+LMB which does the 2nd part of the sequence and switches back to layer 1.
That is the most that I can think of at the moment but if anyone have some questions about some setting I'll be happy to explain further
